Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells

Increased apoptosis and premature cellular ageing of the diabetic heart underpin the development of diabetic heart disease. The molecular mechanisms underlying these pathologies are still unclear. Here we determined the role of pro-senescence microRNA (miR)-34a in accelerating the ageing of the diab...

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Detalles Bibliográficos
Autores principales: Fomison-Nurse, Ingrid, Saw, Eugene Eng Leng, Gandhi, Sophie, Munasinghe, Pujika Emani, Van Hout, Isabelle, Williams, Michael J. A, Galvin, Ivor, Bunton, Richard, Davis, Philip, Cameron, Vicky, Katare, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030067/
https://www.ncbi.nlm.nih.gov/pubmed/29302057
http://dx.doi.org/10.1038/s41418-017-0047-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030067/
https://www.ncbi.nlm.nih.gov/pubmed/29302057
http://dx.doi.org/10.1038/s41418-017-0047-6

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