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Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells
Increased apoptosis and premature cellular ageing of the diabetic heart underpin the development of diabetic heart disease. The molecular mechanisms underlying these pathologies are still unclear. Here we determined the role of pro-senescence microRNA (miR)-34a in accelerating the ageing of the diab...
Autores principales: | Fomison-Nurse, Ingrid, Saw, Eugene Eng Leng, Gandhi, Sophie, Munasinghe, Pujika Emani, Van Hout, Isabelle, Williams, Michael J. A, Galvin, Ivor, Bunton, Richard, Davis, Philip, Cameron, Vicky, Katare, Rajesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030067/ https://www.ncbi.nlm.nih.gov/pubmed/29302057 http://dx.doi.org/10.1038/s41418-017-0047-6 |
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