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SOX17 restrains proliferation and tumor formation by down-regulating activity of the Wnt/β-catenin signaling pathway via trans-suppressing β-catenin in cervical cancer

The SRY-box containing gene 17 (SOX17) is considered as a regulator in stemness maintenance and a suppressor in some malignant tumors. However, the biological function and molecular mechanism of SOX17 in the process of initiation and progression of cervical cancer remain obscure. In this study, immu...

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Detalles Bibliográficos
Autores principales: Li, Lu, Yang, Wen-Ting, Zheng, Peng-Sheng, Liu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030085/
https://www.ncbi.nlm.nih.gov/pubmed/29970906
http://dx.doi.org/10.1038/s41419-018-0782-8