Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

Novofumigatonin (1), isolated from the fungus Aspergillus novofumigatus, is a heavily oxygenated meroterpenoid containing a unique orthoester moiety. Despite the wide distribution of orthoesters in nature and their biological importance, little is known about the biogenesis of orthoesters. Here we s...

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Detalles Bibliográficos
Autores principales: Matsuda, Yudai, Bai, Tongxuan, Phippen, Christopher B. W., Nødvig, Christina S., Kjærbølling, Inge, Vesth, Tammi C., Andersen, Mikael R., Mortensen, Uffe H., Gotfredsen, Charlotte H., Abe, Ikuro, Larsen, Thomas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030086/
https://www.ncbi.nlm.nih.gov/pubmed/29968715
http://dx.doi.org/10.1038/s41467-018-04983-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030086/
https://www.ncbi.nlm.nih.gov/pubmed/29968715
http://dx.doi.org/10.1038/s41467-018-04983-2

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