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Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
Novofumigatonin (1), isolated from the fungus Aspergillus novofumigatus, is a heavily oxygenated meroterpenoid containing a unique orthoester moiety. Despite the wide distribution of orthoesters in nature and their biological importance, little is known about the biogenesis of orthoesters. Here we s...
Autores principales: | Matsuda, Yudai, Bai, Tongxuan, Phippen, Christopher B. W., Nødvig, Christina S., Kjærbølling, Inge, Vesth, Tammi C., Andersen, Mikael R., Mortensen, Uffe H., Gotfredsen, Charlotte H., Abe, Ikuro, Larsen, Thomas O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030086/ https://www.ncbi.nlm.nih.gov/pubmed/29968715 http://dx.doi.org/10.1038/s41467-018-04983-2 |
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