Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion

Centrosome aberrations disrupt tissue architecture and may confer invasive properties to cancer cells. Here we show that structural centrosome aberrations, induced by overexpression of either Ninein-like protein (NLP) or CEP131/AZI1, sensitize polarized mammalian epithelia to basal cell extrusion. W...

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Detalles Bibliográficos
Autores principales: Ganier, Olivier, Schnerch, Dominik, Nigg, Erich A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030118/
https://www.ncbi.nlm.nih.gov/pubmed/29899122
http://dx.doi.org/10.1098/rsob.180044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030118/
https://www.ncbi.nlm.nih.gov/pubmed/29899122
http://dx.doi.org/10.1098/rsob.180044

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