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Antibody responses to α-Gal in African children vary with age and site and are associated with malaria protection

Naturally-acquired antibody responses to malaria parasites are not only directed to protein antigens but also to carbohydrates on the surface of Plasmodium protozoa. Immunoglobulin M responses to α-galactose (α-Gal) (Galα1-3Galβ1-4GlcNAc-R)-containing glycoconjugates have been associated with protec...

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Detalles Bibliográficos
Autores principales: Aguilar, Ruth, Ubillos, Itziar, Vidal, Marta, Balanza, Núria, Crespo, Núria, Jiménez, Alfons, Nhabomba, Augusto, Jairoce, Chenjerai, Dosoo, David, Gyan, Ben, Ayestaran, Aintzane, Sanz, Hèctor, Campo, Joseph J., Gómez-Pérez, Gloria P., Izquierdo, Luis, Dobaño, Carlota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030195/
https://www.ncbi.nlm.nih.gov/pubmed/29968771
http://dx.doi.org/10.1038/s41598-018-28325-w