Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

The succinate receptor 1 (SUCNR1) is a receptor for the metabolite succinate, which functions as a metabolic stress signal in the liver, kidney, adipose tissue and the retina. However, potent non-metabolite tool compounds are needed to reveal the physiological role and pharmacological potential of S...

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Detalles Bibliográficos
Autores principales: Rexen Ulven, Elisabeth, Trauelsen, Mette, Brvar, Matjaz, Lückmann, Michael, Bielefeldt, Line Ø., Jensen, Lisa K. I., Schwartz, Thue W., Frimurer, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030209/
https://www.ncbi.nlm.nih.gov/pubmed/29968758
http://dx.doi.org/10.1038/s41598-018-28263-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030209/
https://www.ncbi.nlm.nih.gov/pubmed/29968758
http://dx.doi.org/10.1038/s41598-018-28263-7

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