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Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
The succinate receptor 1 (SUCNR1) is a receptor for the metabolite succinate, which functions as a metabolic stress signal in the liver, kidney, adipose tissue and the retina. However, potent non-metabolite tool compounds are needed to reveal the physiological role and pharmacological potential of S...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030209/ https://www.ncbi.nlm.nih.gov/pubmed/29968758 http://dx.doi.org/10.1038/s41598-018-28263-7 |