Switchable genome editing via genetic code expansion

Multiple applications of genome editing by CRISPR-Cas9 necessitate stringent regulation and Cas9 variants have accordingly been generated whose activity responds to small ligands, temperature or light. However, these approaches are often impracticable, for example in clinical therapeutic genome edit...

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Detalles Bibliográficos
Autores principales: Suzuki, Toru, Asami, Maki, Patel, Sanjay G., Luk, Louis Y. P., Tsai, Yu-Hsuan, Perry, Anthony C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030211/
https://www.ncbi.nlm.nih.gov/pubmed/29968790
http://dx.doi.org/10.1038/s41598-018-28178-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030211/
https://www.ncbi.nlm.nih.gov/pubmed/29968790
http://dx.doi.org/10.1038/s41598-018-28178-3

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