Mini-hemagglutinin vaccination induces cross-reactive antibodies in pre-exposed NHP that protect mice against lethal influenza challenge

Seasonal vaccines are currently the most effective countermeasure against influenza. However, seasonal vaccines are only effective against strains closely related to the influenza strains contained in the vaccine. Recently a new hemagglutinin (HA) stem-based antigen, the so-called “mini-HA”, has bee...

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Detalles Bibliográficos
Autores principales: van der Lubbe, Joan E. M., Huizingh, Jeroen, Verspuij, Johan W. A., Tettero, Lisanne, Schmit-Tillemans, Sonja P. R., Mooij, Petra, Mortier, Daniella, Koopman, Gerrit, Bogers, Willy M. J. M., Dekking, Liesbeth, Meijberg, Wim, Kwaks, Ted, Brandenburg, Boerries, Tolboom, Jeroen T. B. M., Schuitemaker, Hanneke, Roozendaal, Ramon, Kuipers, Harmjan, Zahn, Roland C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030213/
https://www.ncbi.nlm.nih.gov/pubmed/29977611
http://dx.doi.org/10.1038/s41541-018-0063-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030213/
https://www.ncbi.nlm.nih.gov/pubmed/29977611
http://dx.doi.org/10.1038/s41541-018-0063-7

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