Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the past decade despite evidence of high-grade chloroquine resistance. Here we investigate the genetic changes in a P. vivax population approaching elimination in 51 isolates from Sabah, Malaysia and compare these wit...

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Detalles Bibliográficos
Autores principales: Auburn, Sarah, Benavente, Ernest D., Miotto, Olivo, Pearson, Richard D., Amato, Roberto, Grigg, Matthew J., Barber, Bridget E., William, Timothy, Handayuni, Irene, Marfurt, Jutta, Trimarsanto, Hidayat, Noviyanti, Rintis, Sriprawat, Kanlaya, Nosten, Francois, Campino, Susana, Clark, Taane G., Anstey, Nicholas M., Kwiatkowski, Dominic P., Price, Ric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030216/
https://www.ncbi.nlm.nih.gov/pubmed/29968722
http://dx.doi.org/10.1038/s41467-018-04965-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030216/
https://www.ncbi.nlm.nih.gov/pubmed/29968722
http://dx.doi.org/10.1038/s41467-018-04965-4

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