MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. In order to investigate a new treatment fot GIST, we hypothesized the effect of miR-374b targeting PTEN gene-mediated PI3K/Akt signal transduction pathway on proliferation and apoptosis...

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Detalles Bibliográficos
Autores principales: Long, Zi-Wen, Wu, Jiang-Hong, Cai-Hong, Wang, Ya-Nong, Zhou, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030239/
https://www.ncbi.nlm.nih.gov/pubmed/29902839
http://dx.doi.org/10.14348/molcells.2018.2211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030239/
https://www.ncbi.nlm.nih.gov/pubmed/29902839
http://dx.doi.org/10.14348/molcells.2018.2211

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