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Metal-free selective mono-halodecarboxylation of heteroarenes under mild conditions

The halodecarboxylation of heteroarene carboxylic acids by treatment with N-bromosuccinimide or N-chlorosuccinimide was performed. This procedure provides a convenient route to synthetically useful mono-halogenated heteroarene intermediates such as halo-indoles, -aza-indoles, -indazoles and -aza-ind...

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Detalles Bibliográficos
Autores principales: Henderson, Scott H., West, Ryan A., Ward, Simon E., Honey, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030312/
https://www.ncbi.nlm.nih.gov/pubmed/30110478
http://dx.doi.org/10.1098/rsos.180333