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Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice

Statins are the preferred therapy to treat hypercholesterolemia. Their main action consists of inhibiting the cholesterol biosynthesis pathway. Previous studies report mitochondrial oxidative stress and membrane permeability transition (MPT) of several experimental models submitted to diverse statin...

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Detalles Bibliográficos
Autores principales: Marques, Ana C., Busanello, Estela N. B., de Oliveira, Diogo N., Catharino, Rodrigo R., Oliveira, Helena C. F., Vercesi, Anibal E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030358/
https://www.ncbi.nlm.nih.gov/pubmed/29997512
http://dx.doi.org/10.3389/fphar.2018.00685