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Epigenetic silencing of tumor suppressor gene CDKN1A by oncogenic long non-coding RNA SNHG1 in cholangiocarcinoma

Cholangiocarcinoma (CCA) is the as the most frequently observed biliary tract malignancy, which has low survival rate in addition to constrained treatment options; nevertheless, the fundamental molecular phenomenon underlying malignant progression of CCA is quite ambiguous. Recently long non-coding...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Zhang, Mingjiong, Wang, Ni, Li, Quanpeng, Yang, Jian, Yan, Shuai, He, Xuezhi, Ji, Guozhong, Miao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030364/
https://www.ncbi.nlm.nih.gov/pubmed/29970899
http://dx.doi.org/10.1038/s41419-018-0768-6