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Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice

BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibrosis usi...

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Detalles Bibliográficos
Autores principales: Choi, Arum, Nam, Sun Ah, Kim, Wan-Young, Park, Sang Hee, Kim, Hyang, Yang, Chul Woo, Kim, Jin, Kim, Yong Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030409/
https://www.ncbi.nlm.nih.gov/pubmed/28602064
http://dx.doi.org/10.3904/kjim.2016.230