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Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice
BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibrosis usi...
Autores principales: | Choi, Arum, Nam, Sun Ah, Kim, Wan-Young, Park, Sang Hee, Kim, Hyang, Yang, Chul Woo, Kim, Jin, Kim, Yong Kyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030409/ https://www.ncbi.nlm.nih.gov/pubmed/28602064 http://dx.doi.org/10.3904/kjim.2016.230 |
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