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Recent advances in the diagnosis and management of primary myelofibrosis

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) in which dysregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathways is the major pathogenic mechanism. Most patients with PMF carry a driver mutation in the JAK2, MPL (myeloprol...

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Detalles Bibliográficos
Autores principales: Takenaka, Katsuto, Shimoda, Kazuya, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030412/
https://www.ncbi.nlm.nih.gov/pubmed/29665657
http://dx.doi.org/10.3904/kjim.2018.033