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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumors
As oxygen is essential for many metabolic pathways, tumor hypoxia may impair cancer cell proliferation (1–4). However, the limiting metabolites for proliferation under hypoxia and in tumors are unknown. Here, we assessed proliferation of a collection of cancer cells upon inhibition of the mitochondr...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030478/ https://www.ncbi.nlm.nih.gov/pubmed/29941933 http://dx.doi.org/10.1038/s41556-018-0118-z |