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Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate

Type-2 immunity is regulated by two distinct CD4+ T cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. T helper type-2 (Th2) cells orchestrate type-2 inflammation in peripheral tissues, such as the lung and intestine. Given the importance of Notc...

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Detalles Bibliográficos
Autores principales: Dell'Aringa, Mark, Reinhardt, R. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030499/
https://www.ncbi.nlm.nih.gov/pubmed/29467447
http://dx.doi.org/10.1038/s41385-018-0012-9