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Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques

It is unknown whether the gut microbiome affects HIV transmission. In our recent SHIV vaccine study, we found that the naïve rhesus macaques from two different sources had significantly different rates of infection against repeated low-dose intrarectal challenge with SHIVSF162P4 virus. Exploring cau...

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Detalles Bibliográficos
Autores principales: Sui, Yongjun, Dzutsev, Amiran, Venzon, David, Frey, Blake, Thovarai, Vishal, Trinchieri, Giorgio, Berzofsky, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030500/
https://www.ncbi.nlm.nih.gov/pubmed/29858581
http://dx.doi.org/10.1038/s41385-018-0029-0