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SAVER: Gene expression recovery for single-cell RNA sequencing

In single-cell RNA sequencing (scRNA-seq) studies, only a small fraction of the transcripts present in each cell are sequenced. This leads to unreliable quantification of lowly and moderately expressed genes which hinders downstream analysis. To address this challenge, we introduce SAVER (Single-cel...

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Detalles Bibliográficos
Autores principales: Huang, Mo, Wang, Jingshu, Torre, Eduardo, Dueck, Hannah, Shaffer, Sydney, Bonasio, Roberto, Murray, John I., Raj, Arjun, Li, Mingyao, Zhang, Nancy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030502/
https://www.ncbi.nlm.nih.gov/pubmed/29941873
http://dx.doi.org/10.1038/s41592-018-0033-z