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SAVER: Gene expression recovery for single-cell RNA sequencing
In single-cell RNA sequencing (scRNA-seq) studies, only a small fraction of the transcripts present in each cell are sequenced. This leads to unreliable quantification of lowly and moderately expressed genes which hinders downstream analysis. To address this challenge, we introduce SAVER (Single-cel...
Autores principales: | Huang, Mo, Wang, Jingshu, Torre, Eduardo, Dueck, Hannah, Shaffer, Sydney, Bonasio, Roberto, Murray, John I., Raj, Arjun, Li, Mingyao, Zhang, Nancy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030502/ https://www.ncbi.nlm.nih.gov/pubmed/29941873 http://dx.doi.org/10.1038/s41592-018-0033-z |
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