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Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma

Resident memory CD8 T (T(RM)) cells in the lung parenchyma (LP) and airways provide heterologous protection against influenza virus challenge. However, scant knowledge exists regarding factors necessary to establish and maintain lung CD8 T(RM). Here we demonstrate that, in contrast to mechanisms des...

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Detalles Bibliográficos
Autores principales: McMaster, Sean R., Wein, Alexander N., Dunbar, Paul R., Hayward, Sarah L., Cartwright, Emily K., Denning, Timothy L., Kohlmeier, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030505/
https://www.ncbi.nlm.nih.gov/pubmed/29453412
http://dx.doi.org/10.1038/s41385-018-0003-x