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Mathematical model of a serine integrase-controlled toggle switch with a single input

Dual-state genetic switches that can change their state in response to input signals can be used in synthetic biology to encode memory and control gene expression. A transcriptional toggle switch (TTS), with two mutually repressing transcription regulators, was previously used for switching between...

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Detalles Bibliográficos
Autores principales: Pokhilko, Alexandra, Ebenhöh, Oliver, Stark, W. Marshall, Colloms, Sean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030632/
https://www.ncbi.nlm.nih.gov/pubmed/29875284
http://dx.doi.org/10.1098/rsif.2018.0160