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The relative fitness of drug-resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru

The relative fitness of drug-resistant versus susceptible bacteria in an environment dictates resistance prevalence. Estimates for the relative fitness of resistant Mycobacterium tuberculosis (Mtb) strains are highly heterogeneous and mostly derived from in vitro experiments. Measuring fitness in th...

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Detalles Bibliográficos
Autores principales: Knight, Gwenan M., Zimic, Mirko, Funk, Sebastian, Gilman, Robert H., Friedland, Jon S., Grandjean, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030636/
https://www.ncbi.nlm.nih.gov/pubmed/29950511
http://dx.doi.org/10.1098/rsif.2018.0025