Dual role of USP30 in controlling basal pexophagy and mitophagy

USP30 is an integral protein of the outer mitochondrial membrane that counteracts PINK1 and Parkin‐dependent mitophagy following acute mitochondrial depolarisation. Here, we use two distinct mitophagy reporter systems to reveal tonic suppression by USP30, of a PINK1‐dependent component of basal mito...

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Detalles Bibliográficos
Autores principales: Marcassa, Elena, Kallinos, Andreas, Jardine, Jane, Rusilowicz‐Jones, Emma V, Martinez, Aitor, Kuehl, Sandra, Islinger, Markus, Clague, Michael J, Urbé, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030704/
https://www.ncbi.nlm.nih.gov/pubmed/29895712
http://dx.doi.org/10.15252/embr.201745595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030704/
https://www.ncbi.nlm.nih.gov/pubmed/29895712
http://dx.doi.org/10.15252/embr.201745595

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