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The inhibitory effect of LPS on the expression of GPR81 lactate receptor in blood-brain barrier model in vitro
BACKGROUND: Lipopolysaccharide (LPS) is one of the main constituents of the cell wall of gram-negative bacteria. As an endotoxin, LPS induces neuroinflammation, which is associated with the blood-brain barrier impairment. Lactate is a metabolite with some significant physiological functions within t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030740/ https://www.ncbi.nlm.nih.gov/pubmed/29973231 http://dx.doi.org/10.1186/s12974-018-1233-2 |