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The inhibitory effect of LPS on the expression of GPR81 lactate receptor in blood-brain barrier model in vitro
BACKGROUND: Lipopolysaccharide (LPS) is one of the main constituents of the cell wall of gram-negative bacteria. As an endotoxin, LPS induces neuroinflammation, which is associated with the blood-brain barrier impairment. Lactate is a metabolite with some significant physiological functions within t...
Autores principales: | Boitsova, Elizaveta B., Morgun, Andrey V., Osipova, Elena D., Pozhilenkova, Elena A., Martinova, Galina P., Frolova, Olga V., Olovannikova, Raissa Ya, Tohidpour, Abolghasem, Gorina, Yana V., Panina, Yulia A., Salmina, Alla B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030740/ https://www.ncbi.nlm.nih.gov/pubmed/29973231 http://dx.doi.org/10.1186/s12974-018-1233-2 |
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