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Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle

BACKGROUND: Klotho is a well-known anti-aging hormone, which serves as a suppressor of aging through a variety of mechanisms. Aging of skeletal muscle is concomitant with a decrease in muscle stem cell function resulting in impaired regeneration. METHODS: Here we investigate the functional role of t...

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Detalles Bibliográficos
Autores principales: Ahrens, Hellen E., Huettemeister, Judith, Schmidt, Manuel, Kaether, Christoph, von Maltzahn, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030782/
https://www.ncbi.nlm.nih.gov/pubmed/29973273
http://dx.doi.org/10.1186/s13395-018-0166-x