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Rotavirus-Specific Immunoglobulin A Responses Are Impaired and Serve as a Suboptimal Correlate of Protection Among Infants in Bangladesh

BACKGROUND: Rotavirus (RV)–specific immunoglobulin A (IgA) responses following oral RV vaccination are impaired in low-income countries, where the utility of RV-IgA as a correlate of protection (CoP) remains unclear. In a monovalent oral RV vaccine (Rotarix) efficacy trial among infants in Dhaka, Ba...

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Detalles Bibliográficos
Autores principales: Lee, Benjamin, Carmolli, Marya, Dickson, Dorothy M, Colgate, E Ross, Diehl, Sean A, Uddin, Muhammad Ikhtear, Islam, Shahidul, Hossain, Motaher, Rafique, Tanzeem Ahmed, Bhuiyan, Taufiqur Rahman, Alam, Masud, Nayak, Uma, Mychaleckyj, Josyf C, McNeal, Monica M, Petri, William A, Qadri, Firdausi, Haque, Rashidul, Kirkpatrick, Beth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030840/
https://www.ncbi.nlm.nih.gov/pubmed/29394355
http://dx.doi.org/10.1093/cid/ciy076