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netReg: network-regularized linear models for biological association studies

SUMMARY: Modelling biological associations or dependencies using linear regression is often complicated when the analyzed data-sets are high-dimensional and less observations than variables are available (n ≪ p). For genomic data-sets penalized regression methods have been applied settling this issu...

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Detalles Bibliográficos
Autores principales: Dirmeier, Simon, Fuchs, Christiane, Mueller, Nikola S, Theis, Fabian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030897/
https://www.ncbi.nlm.nih.gov/pubmed/29077797
http://dx.doi.org/10.1093/bioinformatics/btx677