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geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data

Identifying resistance to antiretroviral drugs is crucial for ensuring the successful treatment of patients infected with viruses such as human immunodeficiency virus (HIV) or hepatitis C virus (HCV). In contrast to Sanger sequencing, next-generation sequencing (NGS) can detect resistance mutations...

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Detalles Bibliográficos
Autores principales: Döring, Matthias, Büch, Joachim, Friedrich, Georg, Pironti, Alejandro, Kalaghatgi, Prabhav, Knops, Elena, Heger, Eva, Obermeier, Martin, Däumer, Martin, Thielen, Alexander, Kaiser, Rolf, Lengauer, Thomas, Pfeifer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031006/
https://www.ncbi.nlm.nih.gov/pubmed/29718426
http://dx.doi.org/10.1093/nar/gky349