Cancer progression models and fitness landscapes: a many-to-many relationship

MOTIVATION: The identification of constraints, due to gene interactions, in the order of accumulation of mutations during cancer progression can allow us to single out therapeutic targets. Cancer progression models (CPMs) use genotype frequency data from cross-sectional samples to identify these con...

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Detalles Bibliográficos
Autor principal: Diaz-Uriarte, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031050/
https://www.ncbi.nlm.nih.gov/pubmed/29048486
http://dx.doi.org/10.1093/bioinformatics/btx663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031050/
https://www.ncbi.nlm.nih.gov/pubmed/29048486
http://dx.doi.org/10.1093/bioinformatics/btx663

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