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DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
Proteins are highly dynamic molecules, whose function is intrinsically linked to their molecular motions. Despite the pivotal role of protein dynamics, their computational simulation cost has led to most structure-based approaches for assessing the impact of mutations on protein structure and functi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031064/ https://www.ncbi.nlm.nih.gov/pubmed/29718330 http://dx.doi.org/10.1093/nar/gky300 |