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Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes

Epithelial-mesenchymal transition (EMT) is a major event during cancer progression and metastasis; however, the definitive role of EMT in remodeling tumor microenvironments (TMEs) is unclear. Tumor-associated macrophages (TAMs) are a major type of host immune cells in TMEs, and they perform a wide r...

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Detalles Bibliográficos
Autores principales: Hsieh, Chia-Hsin, Tai, Shyh-Kuan, Yang, Muh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031090/
https://www.ncbi.nlm.nih.gov/pubmed/29981499
http://dx.doi.org/10.1016/j.neo.2018.06.004