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Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) plays an important role in the progression of renal interstitial fibrosis, which finally leads to renal failure. Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with unilateral...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031099/ https://www.ncbi.nlm.nih.gov/pubmed/29973206 http://dx.doi.org/10.1186/s12906-018-2265-y |