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Teriflunomide attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations

BACKGROUND: Genetically caused neurological disorders of the central nervous system (CNS) are mostly characterized by poor or even fatal clinical outcome and few or no causative treatments are available. Often, these disorders are associated with low-grade, disease-promoting inflammation, another fe...

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Detalles Bibliográficos
Autores principales: Groh, Janos, Hörner, Michaela, Martini, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031103/
https://www.ncbi.nlm.nih.gov/pubmed/29970109
http://dx.doi.org/10.1186/s12974-018-1228-z