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Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses
INTRODUCTION: Current models posit a sequence of amyloid β (Aβ), tau, atrophy, and cognitive change leading to Alzheimer's disease, but ambiguities remain. We examined these sequences via serial mediations. METHODS: We studied normal controls, early mild cognitive impairment, and late mild cogn...
Autores principales: | Fletcher, Evan, Filshtein, Teresa Jenica, Harvey, Danielle, Renaud, Alice, Mungas, Dan, DeCarli, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031152/ https://www.ncbi.nlm.nih.gov/pubmed/29984299 http://dx.doi.org/10.1016/j.dadm.2018.04.001 |
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