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Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

BACKGROUND: Upregulated fibroblast growth factor 19 (FGF19) expression in human hepatocellular carcinoma (HCC) specimens is associated with tumor progression and poor prognosis. Nonalcoholic steatohepatitis (NASH) patients are at high risk for malignant transformation into HCC. METHODS: A steatohepa...

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Detalles Bibliográficos
Autores principales: Cui, Guozhen, Martin, Robert C., Jin, Hang, Liu, Xingkai, Pandit, Harshul, Zhao, Hengjun, Cai, Lu, Zhang, Ping, Li, Wei, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031179/
https://www.ncbi.nlm.nih.gov/pubmed/29973237
http://dx.doi.org/10.1186/s13046-018-0781-8