Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy

Tumor-tropic neural stem cells (NSCs) can be engineered to localize gene therapies to invasive brain tumors. However, like other stem cell-based therapies, survival of therapeutic NSCs after transplantation is currently suboptimal. One approach to prolonging cell survival is to transiently overexpre...

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Detalles Bibliográficos
Autores principales: Mooney, Rachael, Majid, Asma Abdul, Mota, Daniel, He, Adam, Aramburo, Soraya, Flores, Linda, Covello-Batalla, Jennifer, Machado, Diana, Gonzaga, Joanna, Aboody, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031202/
https://www.ncbi.nlm.nih.gov/pubmed/30026762
http://dx.doi.org/10.1155/2018/7047496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031202/
https://www.ncbi.nlm.nih.gov/pubmed/30026762
http://dx.doi.org/10.1155/2018/7047496

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