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Cardiac myosin-binding protein C is a novel marker of myocardial injury and fibrosis in aortic stenosis

OBJECTIVE: Cardiac myosin-binding protein C (cMyC) is an abundant sarcomeric protein and novel highly specific marker of myocardial injury. Myocyte death characterises the transition from hypertrophy to replacement myocardial fibrosis in advanced aortic stenosis. We hypothesised that serum cMyC conc...

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Detalles Bibliográficos
Autores principales: Anand, Atul, Chin, Calvin, Shah, Anoop S V, Kwiecinski, Jacek, Vesey, Alex, Cowell, Joanna, Weber, Ekkehard, Kaier, Thomas, Newby, David E, Dweck, Marc, Marber, Michael S, Mills, Nicholas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031261/
https://www.ncbi.nlm.nih.gov/pubmed/29196542
http://dx.doi.org/10.1136/heartjnl-2017-312257