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The somatic mutation landscape of premalignant colorectal adenoma

OBJECTIVE: There are few studies which characterised the molecular alterations in premalignant colorectal adenomas. Our major goal was to establish colorectal adenoma genome atlas and identify molecular markers of progression from colorectal adenoma to adenocarcinoma. DESIGN: Whole-exome sequencing...

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Detalles Bibliográficos
Autores principales: Lin, Shu-Hong, Raju, Gottumukkala S, Huff, Chad, Ye, Yuanqing, Gu, Jian, Chen, Jiun-Sheng, Hildebrandt, Michelle A T, Liang, Han, Menter, David G, Morris, Jeffery, Hawk, Ernest, Stroehlein, John R, Futreal, Andrew, Kopetz, Scott, Mishra, Lopa, Wu, Xifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031265/
https://www.ncbi.nlm.nih.gov/pubmed/28607096
http://dx.doi.org/10.1136/gutjnl-2016-313573