The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Transcriptional enhancers function as docking platforms for combinations of transcription factors to control gene expression. How enhancer sequences determine nucleosome occupancy, transcription factor recruitment, and transcriptional activation in vivo remains unclear. Using ATAC-seq across a panel...

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Detalles Bibliográficos
Autores principales: Jacobs, Jelle, Atkins, Mardelle, Davie, Kristofer, Imrichova, Hana, Romanelli, Lucia, Christiaens, Valerie, Hulselmans, Gert, Potier, Delphine, Wouters, Jasper, Taskiran, Ibrahim Ihsan, Paciello, Giulia, González-Blas, Carmen Bravo, Koldere, Duygu, Aibar, Sara, Halder, Georg, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031307/
https://www.ncbi.nlm.nih.gov/pubmed/29867222
http://dx.doi.org/10.1038/s41588-018-0140-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031307/
https://www.ncbi.nlm.nih.gov/pubmed/29867222
http://dx.doi.org/10.1038/s41588-018-0140-x

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