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Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins

Liquid–liquid phase separation enables compartmentalization of biomolecules in cells, notably RNA and associated proteins in the nucleus. Besides having critical functions in RNA processing, there is a major interest in deciphering the molecular mechanisms of compartmentalization orchestrated by RNA...

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Detalles Bibliográficos
Autores principales: Maucuer, Alexandre, Desforges, Bénédicte, Joshi, Vandana, Boca, Mirela, Kretov, Dmitry A., Hamon, Loic, Bouhss, Ahmed, Curmi, Patrick A., Pastré, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031325/
https://www.ncbi.nlm.nih.gov/pubmed/29728455
http://dx.doi.org/10.1242/jcs.214692