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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the drug and the cytotoxic effect in patients. Here,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031354/ https://www.ncbi.nlm.nih.gov/pubmed/29752286 http://dx.doi.org/10.1242/dmm.033506 |