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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the drug and the cytotoxic effect in patients. Here,...

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Detalles Bibliográficos
Autores principales: García-Rodríguez, Francisco Javier, Martínez-Fernández, Carmen, Brena, David, Kukhtar, Dmytro, Serrat, Xènia, Nadal, Ernest, Boxem, Mike, Honnen, Sebastian, Miranda-Vizuete, Antonio, Villanueva, Alberto, Cerón, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031354/
https://www.ncbi.nlm.nih.gov/pubmed/29752286
http://dx.doi.org/10.1242/dmm.033506