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Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull

The bones of the cranial vault are formed directly from mesenchymal cells through intramembranous ossification rather than via a cartilage intermediate. Formation and growth of the skull bones involves the interaction of multiple cell-cell signaling pathways, with fibroblast growth factors (FGFs) an...

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Detalles Bibliográficos
Autores principales: Schmidt, Linnea, Taiyab, Aftab, Melvin, Vida Senkus, Jones, Kenneth L., Williams, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031357/
https://www.ncbi.nlm.nih.gov/pubmed/29752281
http://dx.doi.org/10.1242/dmm.031526