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Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull
The bones of the cranial vault are formed directly from mesenchymal cells through intramembranous ossification rather than via a cartilage intermediate. Formation and growth of the skull bones involves the interaction of multiple cell-cell signaling pathways, with fibroblast growth factors (FGFs) an...
Autores principales: | Schmidt, Linnea, Taiyab, Aftab, Melvin, Vida Senkus, Jones, Kenneth L., Williams, Trevor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031357/ https://www.ncbi.nlm.nih.gov/pubmed/29752281 http://dx.doi.org/10.1242/dmm.031526 |
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