A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disorder caused by mutations in the dystrophin gene, with an incidence of 1 in 3500 in new male births. Mdx mice are widely used as an animal model for DMD. However, these mice do not faithfully recapitulate DMD patients in many aspects...

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Detalles Bibliográficos
Autores principales: Sui, Tingting, Lau, Yeh Siang, Liu, Di, Liu, Tingjun, Xu, Li, Gao, Yandi, Lai, Liangxue, Li, Zhanjun, Han, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031364/
https://www.ncbi.nlm.nih.gov/pubmed/29871865
http://dx.doi.org/10.1242/dmm.032201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031364/
https://www.ncbi.nlm.nih.gov/pubmed/29871865
http://dx.doi.org/10.1242/dmm.032201

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